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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Brien, Jason | SP | Wheeling Nailers | 28 | 04/18/2035 | Clearfield | USA | Right | Right | 6' 0" | 195 lbs | $1,120,000 |
| O'Neal, Justin | 3B | Cleveland Cardinals | 29 | 10/24/2033 | Odenton | USA | Right | Right | 6' 4" | 200 lbs | $19,000,000 |
| O'Neil, Jim | C | Oakdale Otters | 17 | 11/23/2045 | Drayton Valley | CAN | Right | Right | 6' 0" | 185 lbs | - |
| Obando, Tony | SP | Roanoke Boomers | 16 | 08/25/2046 | Torreón | MEX | Right | Right | 6' 3" | 180 lbs | - |
| Ochoa, Julio | LF | Schenectady Jaguars | 29 | 03/10/2034 | Caracas | VEN | Left | Left | 6' 1" | 200 lbs | $7,800,000 |
| Ochoa, Marcos | SP | Chesapeake Hurricanes | 17 | 05/25/2046 | Havana | CUB | Right | Right | 6' 7" | 195 lbs | - |
| Odgers, Brian | SP | Indiana Ironmen | 27 | 01/27/2036 | Lake City | USA | Left | Left | 6' 1" | 205 lbs | $950,000 |
| Oettinger, Michaihu | C | Indiana Ironmen | 18 | 12/16/2044 | Rishon LeZion | ISR | Right | Right | 6' 0" | 190 lbs | - |
| Offutt, Justin | RP | Brookline Knights | 27 | 10/30/2035 | Chesapeake | USA | Right | Right | 6' 5" | 200 lbs | $1,260,000 |
| Ogasawara, Masaki | SP | Brookline Knights | 18 | 10/13/2044 | Kurashiki | JPN | Left | Right | 6' 3" | 180 lbs | - |
| Oh, Dong-hyun | SP | Centre County Lions | 17 | 01/09/2046 | Incheon | KOR | Left | Right | 6' 5" | 185 lbs | - |
| Okayama, Rintaro | RP | Clarion Cubs | 29 | 07/11/2033 | Omihachiman | JPN | Right | Right | 6' 4" | 200 lbs | $2,080,000 |
| Okimoto, Hiroshi | 1B | Brooklyn Bashers | 22 | 12/03/2040 | Hanamaki | JPN | Left | Left | 6' 6" | 205 lbs | $555,000 |
| Oldroyd, Harris | SP | Atlantic City Assassins | 17 | 12/28/2045 | Oranjestad | ARU | Left | Left | 5' 10" | 160 lbs | - |
| Olesen, Adam | C | Schenectady Jaguars | 27 | 09/21/2035 | Buffalo | USA | Right | Right | 6' 0" | 200 lbs | $555,000 |
| Olivares, Edward | RF | Baltimore Crusaders | 18 | 08/12/2044 | San Salvador | SLV | Left | Left | 5' 11" | 185 lbs | - |
| Olivarez, Jesus | SP | Erie Lakers | 18 | 03/18/2045 | Bajos de Haina | DOM | Left | Left | 6' 6" | 205 lbs | - |
| Olson, Steve | RP | Benezette Elks | 30 | 03/17/2033 | Naperville | USA | Right | Right | 6' 2" | 195 lbs | $4,680,000 |
| Onishi, Tatsuo | CF | Eaglesmere Eagles | 17 | 07/12/2045 | Fuchu | JPN | Right | Right | 6' 2" | 170 lbs | - |
| Opie, Mike | LF | Baltimore Crusaders | 30 | 03/30/2033 | Melbourne | AUS | Left | Left | 6' 6" | 215 lbs | $555,000 |
| Oram, Shelby | SP | Roanoke Boomers | 16 | 07/30/2046 | Mississauga | CAN | Right | Right | 5' 10" | 155 lbs | - |
| Ortega, Jesus | RP | Wheeling Nailers | 28 | 12/06/2034 | Jiguaní | CUB | Right | Right | 6' 5" | 200 lbs | $555,000 |
| Ortega, Miguel | SS | Wilkes Barre/Scranton Penguins | 17 | 11/02/2045 | Mérida | MEX | Right | Right | 6' 2" | 175 lbs | - |
| Ortiz, Alberto | 1B | Wheeling Nailers | 27 | 03/24/2036 | Philadelphia | USA | Right | Right | 6' 4" | 240 lbs | $555,000 |
| Ortiz, Cesar | SP | Centre County Lions | 16 | 04/21/2047 | San Juan | PUR | Left | Left | 6' 2" | 175 lbs | - |
| Ortiz, Chris | SP | Clearfield Cannonballs | 18 | 03/04/2045 | Morón | CUB | Left | Left | 6' 0" | 165 lbs | - |
| Ortiz, Manny | CF | Brooklyn Bashers | 27 | 12/05/2035 | Bogota | COL | Left | Left | 6' 3" | 200 lbs | $20,200,000 |
| Ortiz, Melvin | CF | Clearfield Cannonballs | 24 | 05/23/2039 | Virginia Beach | USA | Left | Left | 6' 1" | 180 lbs | $555,000 |
| Ortiz, Ramiro | 3B | Hazelwood Harpoons | 31 | 06/18/2032 | Tuxtla Gutiérrez | MEX | Left | Right | 5' 11" | 190 lbs | $1,440,000 |
| Ortiz, Roberto | SP | Schenectady Jaguars | 17 | 11/24/2045 | Güines | CUB | Switch | Right | 6' 3" | 180 lbs | - |
| Oto, Masahiro | 1B | Indiana Ironmen | 17 | 04/02/2046 | Takasaki | JPN | Left | Left | 6' 1" | 195 lbs | - |
| Otsuka, Noriaki | CF | Hazelwood Harpoons | 17 | 02/17/2046 | Karasuyama | JPN | Left | Left | 6' 0" | 160 lbs | - |
| Oviedo, Jesus | C | Cleveland Cardinals | 18 | 07/08/2045 | Calimete | CUB | Right | Right | 6' 4" | 190 lbs | - |
| Oyama, Toru | SP | Buffalo Black Sox | 18 | 02/28/2045 | Mizusawa | JPN | Left | Left | 6' 4" | 185 lbs | - |
| Ozaki, Shigeharu | 2B | Indiana Ironmen | 26 | 09/17/2036 | Tokyo | JPN | Right | Right | 6' 3" | 200 lbs | $555,000 |
